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• CU Boulder research has shown that opposites don't always attract. • Analysis of more than 130 signs showed that partners most often resemble each other. • Only 3% of signs indicate cooperation with those who are different from them. • Research sheds light on the invisible forces that shape human relationships. • The results may distort the results of genetic studies. • A meta-analysis of 22 features across 199 studies showed a high correlation. • Traits associated with substance use showed a high correlation. • Height, weight, health status and personality traits showed a smaller but positive correlation.