I use an RTX 2060 on Fedora and it work very well. Initial setup is not that hard either, just look for instructions in the Fedora docs. And it works mostly perfect on Wayland, but you need to update through GNOME software so the kernel builds the NVIDIA akmod package. Do note though that updating takes longer this way.
Well, NixOS is pretty easy to install using their graphical installer and it has one of the largest package repositories. It has basically everything you could need.