tl;dw if you have childhood trauma, no agency, and no social support you're turbofucked.
he talks about material conditions a little but doesn't name them as such so there's a marxism shaped hole in the analysis but i'd be shocked if a yankee associated with stanford university would get his shit together enough to recognize and then say publicly that socialism would massively reduce the risk of major depression
lot of "hey he's talking about me" and some "what the fuck you mean we do coinflip brain surgeries", plus the best drugs only actually work 1/3 of the time and ohbytheway our serotonin model might be exactly backwards too.