I've gone between the two brands. Samsung strikes me as a little visually complicated whereas Pixel is cleaner and the point with its design choices. Connect ADB and you can disable all of the apps that come with the Samsung if you wish. Don't really prefer OneUI, though it felt snappier with the Snapdragon.

With that said, I enjoyed my Samsung overall, and I'm enjoying my Pixel. I don't think you'll be disappointed, but if I were you, I would reflect on how I feel about a little bit more clutter. It's in the details, like having two account sign in areas for both your Samsung and your Google accounts. Two app stores. The price and stress of more choices.

If you intend to own the device for a long time, consider that you have much better aftermarket solutions on Pixel because Google releases more, higher quality code and drivers makes your ROM devs life much easier. Fewer bugs for you in the aftermarket. You can only run GrapheneOS on a Pixel.