To be fair, I have no idea how to hold one of those. Bit you can bet I'm sure going to check which is the business end before I go stabbing something with it.
An orange is actually fairly easy to hold. It's pretty much the size of a hand. So, unless you have tiny baby hands, I wouldn't worry too much about how to hold them.
They are pretty clearly labeled and when I first got one, it came with a non-needled practice epipen. That's probably something everyone should be exposed to. The needles come out fast and can do some serious damage and the difference between properly using an epipen or wasting it during an emergency can be life or death.
Everytime i see an epipen i think about that scene from horrible bosses when one of the guys stabs the boss 30 times in the chest with the epi pen. https://youtu.be/j8wwNpkpEN0