Half of these exist because I was bored once.
The Windows 10 and MacOS ones are GPU passthrough enabled and what I occasionally use if I have to use a Windows or Mac application. Windows 7 is also GPU enabled, but is more a nostalgia thing than anything.
I think my PopOS VM was originally installed for fun, but I used it along with my Arch Linux, Debian 12 and Testing (I run Testing on host, but I wanted a fresh environment and was too lazy to spin up a Docker or chroot), Ubuntu 23.10 and Fedora to test various software builds and bugs, as I don't like touching normal Ubuntu unless I must.
The Windows Server 2022 one is one I recently spun up to mess with Windows Docker Containers (I have to port an app to Windows, and was looking at that for CI). That all become moot when I found out Github's CI doesn't support Windows Docker containers despite supporting Windows runners (The organization I'm doing it for uses Github, so I have to use it).
I use Debian. Like I said, video is only sometimes choppy. I usually have a few vlc windows open at one time. Something I've learned is that it will use a lot of CPU even if the video is paused. To stop it, I have to manually set the video source to "none" when I pause a video and leave it in the BG.
Or just pause the whole VM. Another great Qubes feature