Apparently there's a plot point that involves Gaia creating the Ratkin to eradicate humanity's "surplus population" through disease, which has some very uncomfortable implications, especially in the light of the gross indifference to human life that the ruling class has exhibited in the wake of Covid-19.
I realize this is hinged on a lot of assumptions (that this information is accurate in-universe and that Gaia, as the personification of the Earth, serves as a mouthpiece for the creators' environmentalist views), which is why I'm asking.
In fairness I could totally imagine running a campaign where a bunch of Brujah communists band up to take down some True Brujah fascist cosplaying as a philosopher king. But I'm pretty sure that's not what they're going for.