uMatrix's interface is amazing and I have yet to find a good replacement on that front. At first I tried NoScript, but I lost my whitelist after a couple months and didn't feel like building it up again, then I tried GNU's script blocker that doesn't block open source scripts (which was helpful for peertube instances because I had to always manually unblock them with noscript) but it was really difficult to know what the scripts actually were with that one. After that I tried uBlock on advanced mode and I'll be honest I don't think I ever fully understood what that did but I went back to uMatrix for the time being because just being able to see the domains and subdomains and the categories all in a grid and easily blockable was really simple and useful for me.