Buddy, you are (unintentionally, I'm sure) repeating some fairly transphobic talking points. How would you feel about a study analyzing the brain structure of gay people to try and search for differences between gay and straight people? Does that seem like a good study to you? Also, your response to silent_water is doing exactly what I hoped you weren't doing when I wrote my last comment to you, namely, you're saying that a trans person telling you to your face that hormones make them feel better, so there must be some biological component to transness sometimes might be, what? Mistaken? Lying? Or maybe you just think that my (and silent_water's) physical response to hormones is somehow mediated through culture? That is the non-transphobic reading of what you've said, but if that's what you believe you're going to have to bring forth some evidence that someone's physical response to a change of hormones could be solely cultural. Because I do not see any possibility that a change to someone's endocrine balance would feel different based purely on social factors.