The actual execution was a mess, but Skullface's inspiration for his parasite weapon being the experience of linguistic imperialism as a child was a really novel premise. The idea that he would get his revenge by creating a weapon that killed anyone who spoke English is some cool super-villain shit I don't think I've ever encountered before. "Race-selective" weapons, genetic-targetting weapons, religious indoctrination viruses, I've seen all those, but I think MGSV is the only time I've encountered a weapon that targets a language community.
Kojima consistently hits near the mark but is given way more credit than due. He has a few cool concepts and accidently came up with post modernism a second time but he's fucking stupid as hell in most ways. Pretty sure if he'd read Lennin he'd have a less cartoonist view of the cold war than he exemplified. A brief look at mgs3, peace walker and 5 shows he had a massively lib brained view of the world and complete and utter historical illiteracy. He is I Am 14 And This Is Deep embodied.