The irreversible global catastrophe is imperialist militaries massacring people with little risk to themselves. 
The irreversible global catastrophe is assembly line robots at the Toyota plant becoming sentient and going on a freaking epic terminator style mass shooting and enslave everyone except me 
I always liked how part of the reason The Sentient from Warframe turned on their creators was because they rightly realized the Orokin were a bunch of crazed immortal hyper-fascists who ruin everything they touch
Well actually that was retconned but then the retcon was retconned so now nothing is confirmed to be true. /s
RIP Corpus Braton