If you use steam, 90+% will just work out of the box with little to no tinkering required. Valve basically singlehandedly made Linux gaming capable with Proton. Often the proton version works better than the native ports, which is kind of sad honestly.
For everything else, it's iffy. GOG installers work relatively often, but piracy is more difficult, because there is always some dependency missing, wine doesn't quite work right, native ports rely on old libraries etc etc.
I use PopOS/Mint (essentially Ubuntu).
If you use steam, 90+% will just work out of the box with little to no tinkering required. Valve basically singlehandedly made Linux gaming capable with Proton. Often the proton version works better than the native ports, which is kind of sad honestly.
For everything else, it's iffy. GOG installers work relatively often, but piracy is more difficult, because there is always some dependency missing, wine doesn't quite work right, native ports rely on old libraries etc etc.