Synth music style invented around 30 years ago on technology that didn't exist a generation ago: "This sounds old-fashioned, the developers need to evolve."
Orchestral music played on instruments that have existed for thousands of years, in a style that's existed for hundreds: "Finally, a modern sounding ost!" 
I think it'd be very out of place in the Mana series of games for the most part.
Even if it wasn't, it'd be boring from sheer saturation.