• Rivalarrival@lemmy.today
    ·
    3 months ago

    Thank you!

    The first link says there are "changes" to the immune system, but doesn't seem to suggest that the immune system is actually weakened.

    I might have missed something, but I'm not seeing anything suggesting that we are more prone to viral or bacterial infection due to COVID. It seems to be saying that immune response is heightened, not weakened. That's not necessarily a good thing either, as an overly aggressive immune system carries its own problems. They seem to suggest that "Long COVID" could be some sort of an autoimmune issue.

      • Rivalarrival@lemmy.today
        ·
        3 months ago

        Thank you for that as well, but again: I'm not seeing support for a claim that COVID trashes the immune aysyem. In that link, like the earlier one, there are observations that suggest both weakened immune response and excessive immune response, both having potentially harmful effects.

        It's one thing to point out that COVID affects the immune system. All three of the above links go well above and beyond my own understanding and comprehension to demonstrate that certain changes to the immune system are occurring. But, what isn't so clear is the actual effects of these changes. They are saying, for example, that they have observed COVID reducing CD8+ T-Cell response, which sounds really bad. But does that reduced response actually translate into a greater susceptibility to infection?

        I guess what I'm asking for is less focus on the tree,.and a broader view of the forest. For example, are there any studies showing the prevalence and severity of non-COVID infections, before and after COVID? What transmissible diseases, if any, have surged concomitant with COVID? Are the micro-scale observations documented in the above links correlated with macro-scale effects?

        Just to be clear, I'm not trying to push an agenda here; I honestly do not know the answers, and the underlying biology is well over my head. When I start repeating the claim that COVID trashes the immune system, I want to know what I mean.

          • Rivalarrival@lemmy.today
            ·
            edit-2
            3 months ago

            I have. I've seen a number of sources all pointing to the same micro-scale observations. What I haven't found is anything showing the macro-scale effects.

            I understand that the trees are changing. Are these changes having a tangible, measurable effect on the forests? Or are these changes just a bit of interesting trivia?

            • JoeByeThen [he/him, they/them]
              ·
              3 months ago

              Oh, no. No. I'm afraid all because of the lockdowns. Definitely not the Covid.

              https://archive.ph/mJiiq

              https://www.health.org.uk/news-and-comment/news/health-foundation-responds-to-ons-update-on-economic-inactivity-due-to-long-term-sickness

              https://icemsg.org/2024/07/21/2024-week-28/

                • JoeByeThen [he/him, they/them]
                  ·
                  3 months ago

                  Welcome. Basically what you wanna look for is historical data on opportunistic infections; Strep, shingles, hepatitis, that sort of stuff. I had a Twitter screenshot showing elevated levels of like 8 of them but can't find the dang thing. As that third link points out Tuberculosis is a good indicator of overall immune health and is heading towards shaky ground.