I'd expect banking apps and other niche but important apps to shit themselves without full Google services. I'd expect something like Magisk to work for a lot of things, but I remember Huawei being kinda shitty about rooting before they were banned in the US, and their software kinda sucked too so replacing it was worth it.

Idk, I'm sure someone is going to make a custom ROM that has everything fixed for the west. Nerds do love Huawei and Honor.