It's essentially just a remote desktop app, so yeah kinda. Depending on your screen resolution it'll be either be more or less annoying to click on smaller UI elements, but it's certainly possible.
I keep my Bluetooth headphones connected to the PC, and there's maybe a split second delay. Otherwise it's perfect, because you can still navigate your PC with the touch screen as a mouse, and it even nicely supports my 3 monitors at once.
Not a serious suggestion, but I can confirm that WACUP does at least have no noticeable issues using WINE