My comment : this study is high quality af
Abstract
Background
Cognitive impairment can be caused by infections with various pathogens, including SARS-CoV-2. Research has yet to determine the true incidence and course of cognitive impairment in older adults following COVID-19. Furthermore, research has theorised that COVID-19 is associated with dementia progression and diagnosis but this association has yet to be fully described.
Methods
A systematic review was registered in Prospero and conducted on the databases PubMed, Embase, Ovid, CENTRAL and Cochrane Library. Studies reporting cognitive impairment and dementia outcomes in post-acute and post-COVID-19 patients aged ≥65 years, and which included control data, were included in this review.
Results
15,124 articles were identified by the search strategy. After eliminating duplicate titles and completing title, abstracts and full-text review, 18 studies were included comprising of 412,957 patients with COVID-19 (46.63 % male) and 411,929 patients without COVID-19 (46.59 % male). The overall mean Montreal Cognitive Assessment (MoCA) score in COVID-19 patients was 23.34 out of 30 (95 % CI [22.24, 24.43]). indicating cognitive impairment. The overall proportion of patients identified as having new onset cognitive impairment was 65 % (95 % CI [44,81]). Subgroup analyses indicated that time since infection significantly improves overall MoCA score and reduces proportion of patients with cognitive impairment.
Conclusion
This study indicates that cognitive impairment may be an important sequela of COVID-19. Further research with adequate sample sizes is warranted regarding COVID-19’s association with new-onset dementia and dementia progression, and the effect of repeat infections. There is a need for development of diagnostic and management protocols for COVID-19 patients with cognitive impairment.
I've been meaning to make a post about it, metformin may help. It's primarily useful to preventing long COVID, but some people with long COVID have found that it has helped their recovery, too.
I've been think we may need to make a post just to collect all the stuff we've run across that may help. Since a lot of us don't have healthcare and are just kinda shooting in the dark anyway.
I think this is a great idea. Maybe an evolving Sticky post, and people can comment with links to research supporting the medications, supplements, behavior change, etc?
Sounds good. @ButtBidet@hexbear.net, thoughts, as a mod? Wanna start it off with a pinned post?
Can do
Thankya thankya.
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