Depends on the ep, and if you're interested in getting some information on a topic you might be interested in with a whole lot of silliness intermixed. But like with anything else, if their sense of humor isn't your thing, it's not gonna click.

I recommend picking an episode that seems to talk about something you think might be interesting and go from there, just go in expecting a fair bit of goofiness and not a hard-facts-only-no-jokes style joint. The Musk episodes were good for exposing exactly what kinds of cons he gets up to, and I intend to go back and listen to them for a refresher since he's somehow still viewed favorably by... people...