For me:
Reasonable:
New Smash character reveal
Some sort of "Zelda All-Stars" collection for the series anniversary
Rerelease of the Four Swords Anniversary Edition also for the aforementioned anniversary
More updates for New Horizons?
Unreasonable:
Remakes/Remasters/Any sort of fucking rerelease of the first 2 Paper Mario games :vivian-shrug:
Super Mario Odyssey 2
Official confirmation of the Switch Pro or whatever it'll be called
Pikmin 4
Nintendo 64/Gamecube Mini
Reasonable:
A bit more info on BOTW 2
A bit more info on Metroid Prime 4, saying it's still not ready enough to announce yet.
A bit more information on the Pokemon Gen IV Remakes
Updated Switch hardware, because they literally can't continue making Switches since Nvidia stopped offering scale pricing on the Tegra X1 and more imporantly will stop producing new X1 chips a bit later this year. Hardware includes some of the rumored SKUs that support higher resolution output and other features, but all of these features are disabled and some 0.1 cent per unit hardware necessary to actually utilise those features is omitted for absolutely no reason.
Another Fire Emblem character confirmed for Smash!
Unreasonable:
Anything more for New Horizons
Super Mario Odyssey 2
Wii Sports for Switch
The Gen IV Remakes being good
The new switch hardware is called the Nintendo Switch Pro and actually involves a noticeable hardware spec bump.