Your only shot is nuclear and mining asteroids, but entering and leaving the gravity well requires rocket fuel. You could make it from the ice at the poles, but that also requires tons of energy and dangerous industrial processes in an already inhospitable atmosphere.

Mars is maybe good as a small research base or stopping point for sending larger missions to other planets. I don't think it'll ever be profitable to do space stuff and any of this will need to be a collective societal drive that we all work for without an expectation of profit.