I can think of some obvious examples to start with, but my subtle but insidious nominee is Fable III. Fittingly for a pretentious grifter like Molyneux, the game requires you to raise a specific amount of gold or your kingdom is destroyed and you get a bad ending. The goalposts are moved by the game if you raise money in ways it doesn't approve of, and it is simply impossible to reach the fundraising goal in any way that isn't at least Enlightened Centrist levels of evil, the kind that lanyard-wearing neoliberals giggle about. That's right, you need to be at least this evil or your kingdom is destroyed. So deep and really makes you think about the hard decisions that are made by the ruling class, doesn't it? :zizek:
I've always thought that the 4X genre could be non-reactionary if it centered around a revolution trying to propagate rather than just states fighting over land and doing imperialism.
One of those Xs stands for "Exterminate", so bad politics is kind of baked in at a fundamental level.
"eXterminate" the bourgeoise.
Anyway, killing everyone else isn't even required for every playstyle in a 4X game.