The melatonin and i-pad time generation is gonna be deeply unwell holy

    • dat_math [they/them]
      ·
      3 years ago

      In https://news.mit.edu/1999/melatonin-1103 , "She also said that one of the trickier aspects of choosing an appropriate dose of melatonin for use as a sleep aid is that "normal" melatonin levels vary widely among individuals and the same dose of the hormone can induce different levels depending on the individual's age or health. She recommends measuring individual melatonin levels, or, if this is not feasible, starting with a tiny dose (0.1 mg) and gradually increasing it until the desired effect is noticed."

      I don't think the SFN publishes their talks and posters as journal articles and I had trouble finding the paper I remembered from my stint as a neuroscience grad student years ago. In that article, they ran an experiment whose goal was identifying minimum effective dosages in humans and came up with 100 micrograms as a dose that works for most people, with the vast majority (i.e., > 95%) of people responding to 300 micrograms.