There's a one minute video with the joke in the tweet.
Aside from from the obvious shit on whether you should wokescold stand-up comedians (of course you should), it made me think about the weird position straight cis dude gender nonconformity has in today's progressive spaces. Like there are people with trans flags in qrts explaining that a straight guy having his nails painted is a bad sign.
Here in Russia when I was growing up you could get beat up for being a guy with painted nails. One time I almost did.
That's definitely the angle, and the way he goes straight into the bit is supposed to emphasize that. Just feels like a setup that deserves more than just a minute of material, I guess.