i can second what other people have said about Inland Empire and the PSYCHE stat block in general, it doesn't necessarily have to be your highest stat but in a first playthrough its probably not something to ignore.

any dialouge option that starts with "wait" or "hang on" won't progress the conversation, they're free clicks to get more infomation/dialogue. don't be afraid in general to pursue some of the more insane lines of thought, explore conversations, and talk to everyone.

and if you take damage on your last hit point, you can use a healing item while the point is depleting by clicking on the little plus sign above your healthbars - i got sent back to my last save a fair few times because i didn't realise that for most of the game lol