I'm immunocompromised and continuing to stay at home and single player games really help me get through it. I've played a lot of games (especially the past 2.5 years), so dig deep and give me a good recommendation that you don't think I've played.
I'm into most genres, but not super into loot games or ubisoft open world style games. Love smaller indie titles. I love some JRPGs (Trails, DQ11, Yakuza, FF), hate others (Persona). Yeah I just said I hate persona, get over it. BoTW , Death Stranding, and Elden Ring are some of my favorite "big" games recently. The Trails JRPG series is probably my favorite overall series.
I just finished up Return to Monkey Island and really liked it (was a big fan of LucasArts adventures in the 90s), but I can't play back to pack point and click games so maybe cool off on that.
Been playing a lot of Ooblets while working out lately, so probably not gonna be receptive to any Animal Crossing / Stardew style games rn. Btw check out Ooblets if you like those kinds of games.
If you like the gameplay in Octopath you'd probably like Star Renegades. Beautiful pixel art there too. Roguelike though if that's a deal breaker.
EDIT: Shoulda said, it has a stunning system that is similar to OT, but you see all enemy attacks for the round and decide all of your own attacks for the round at the start of the round. Your attacks have variable speeds and amounts of both stunning and damage so each round is a puzzle to do as much damage as possible while also stunning enemies to prevent them from damaging your characters (damage persists from fight to fight which is the primary way you ultimately fail a run).