I'd make the case for Ayn Rand in real-world conditions that have been worsened due to her influence. Ayn Rand, Alan Greenspan, and several other dweebs used to have a brain trust "The Ayn Rand Collective" where they sat around and read Atlas Shrugged to each other, simped for Rand, and dreamed up evil shit for when they gained power and could enact it. Alan Greenspan, chairman of the Fed, has probably had more influence on the world than Thatcher as British PM. And while Thatcherism has collapsed and been replaced by new ghoulery there is still the ongoing threat of things like social security privatization and financial deregulation which as concepts crawled directly from Ayn Rand's living room into global economic systems.