agreed, but if its one on one and we are equiv. height (or opponent is a little taller and tucking their chin), my fist is meeting square-on with their face, breaking bone and removing teeth. that location is pretty catastrophic and almost certainly ends the fight.

however breaking shots to the nose (as you discussed) are fantastic and usually blind the opponent with their own involuntary tears, allowing for retreat (sometimes a good option). this is why a nice crisp jab is sometimes all you need.

an addendum: in almost any violent situation, the primary goal is to end the situation and exit with minimal damage. however you manage to achieve this successfully is a win. fight enough and you will find someone with your kryptonite, so avoid fights as much as possible. if its unavoidable, then end the fight as quickly as possible and exit.