I don't think so; at least not in a permanent, static sense of "true self." Anyone who's taken enough DMT or acid knows that the only thing separating your sense of self from everything else is a few molecules of the right chemical cocktail. And so if you reject the idea of a supernatural aspect of "you" existing independent of your body, all you're left with is consciousness being some emergent phenomenon of biology and physics. At best it's a pattern, and one that shifts radically from year to year, moment to moment.