It modulates the response to the virus at the level of the immune system, and is used to treat an infection.

We conducted an experimental protocol with a nasal recombinant IFNα-2b formulation (Nasalferon) in 12 healthy volunteers who received 1 MIU per nostril twice a day, three consecutive days, and studied the induction of biomarkers related to antiviral and immune responses. Nasalferon increases the antiviral biomarker OAS1 transcript levels in oropharynx and PBMCs, regulates molecular and cellular elements related to innate and adaptive immune responses and decreases granulocytes population. These effects support Nasalferon use in virally-exposed populations.

Nasalferon, a new nasal formulation of IFNα2b, modulates cellular and molecular elements associated with an antiviral response in mucosa and blood

Cuba will start applying Nasalferon to travelers and live-in family members

In Cuba, All International Travelers to Receive Nasalferon

An Experience with Cuban Biotech's Nasalferon to Prevent SARS-COV-2 Infections in International Travelers and their Contacts

Meanwhile "free" countries are destroying the lives of millions of people by pretending covid doesn't exist anymore, and paxlovid is $1000 dollars and doctors don't want to prescribe it because covid is "mild".

  • btfod [he/him, comrade/them]
    ·
    10 months ago

    IIRC recombinant drugs are all based on human genes so the recomb proteins aren't really "alien" though I like the rest of the analogy

    • WhatDoYouMeanPodcast [comrade/them]
      ·
      10 months ago

      Sure, you're putting a human gene in there, but the subtle part of it is that when you have to recognize something as foreign, your cells chop up a protein and present IIRC 8-12 amino acids to present for immune cells (mhc-1). In that sense, the body is really sensitive to what proteins look like. I would imagine it not accepting a document that was .pdf instead of .docx. So when the protein is synthesized via recombinant means, I would expect some small change - if not even in terms of AA sequence (which Cuban scientists no doubt had to test for) then some glycosylation or other alterations that a bacteria would do.

      The method isn't brand new or anything, I believe insulin can be made that way (not checking), it's just a marvel of science to me

      • btfod [he/him, comrade/them]
        ·
        10 months ago

        You got me thinking about the different forms of insulin where sequence changes result in different effects... so yeah agreed it's marvelous. Good point