It should be pretty obvious that there's no serious opposition to Biden on the Democratic side.
If you believe in voting for harm reduction in the general, surely the same then must apply to the Republican primary, since voting in the Democratic primary would just be throwing away your vote.
Before this question is misinterpreted, I live in Texas, which is an open primary state, and as it would not be very inconvenient for me to go vote a harm reduction candidate in said primary, I'm seriously considering doing it.
John Kasich