In SuperhotVR there are multiple acts of self harm; Shooting oneself in the head, jumping to your death. They make up a very very small amount of the game's content. After an update which made those scenes optional, the devs did another update and removed them all together. The VR community has surprisingly responded in a very mature and supportive manner.
LOL, just kidding. They're totally shitting themselves. https://old.reddit.com/r/virtualreality/comments/op018r/all_scenes_alluding_to_self_harm_will_be_removed/ https://steamcommunity.com/games/617830/announcements/detail/2992063678829322337
There's been some use of VR in helping people get over PTSD, so I'm kinda inclined to side with the "VR makes things different enough that extra care should be taken" crowd.