Here are some that I can think of:
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Michael Richards- used the n-word multiple times in response to black hecklers during a stand-up performance.
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Roseanne Barr- said Valerie Jarrett, who is partially black, looked like a Planet of the Apes character.
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Gina Carano- compared Joe Biden's policies as President to the Holocaust.
Even then, Carano will be working for The Daily Wire and Barr was doing a stand-up tour prior to the coronavirus pandemic. Also, Richards has made or still does make a lot of money off of Seinfeld and probably could have had a career like Jason Alexander (making the rounds as a television guest star), if he wanted.
Does @nero count?
Yes, I'd say so.
It's amazing how much he dropped off the face of the Earth.
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