A good combination is diabetes and chronic blood clotting issues. The former also contributes to the latter and most diabetics die of clots. If the stroke/heart attack doesn't kill you outright, which won't factor into that coveted 999million9%.999.9%.% survival rate, you'll end up with the other pureblooded survivors competing for nursing home beds or each new degree of debilitation will only increase your clotting risk.

I'd get a booster every day to avoid real COVID.