For the purposes of this post "Straight Edge" means no alcohol, tobacco or recreational drugs. Some definitions take it farther than that, but I just mean the basic one.
But yeah, I'm in my late 20s and have never really seriously partaken myself due to lack of interest. The only times I can recall are accidentally taking a drink of someone's Bloody Mary when I was a kid (Which I still remember was spicy as fuck decades later btw), and getting some 2nd-hand pot smoke at a friend's house once.
If you do, I don't judge, just try to be careful/not overindulge is all I'd say.
I don't like being drunk, I drink somewhat regularly but basically never get actually intoxicated. 1 beer here, half a shot of whiskey there. Being even moderately drunk just makes me sleepy and hurts my stomach., then gives me a headache if I don't force down a lot of water. And even then I get a light headache later.
Weed is pretty cool I guess but when I have purposely smoked a bunch, I'm just kind of sitting there vaguely frustrated that I am absent minded, and unable to articulate anything. I have no desire to actually smoke it. A few hits is kinda nice, I guess, but not that interesting to me.
I also had to take opioids for extremely severe tooth pain, it was amazing how much they numbed the pain but it gave me no desire to take more other than when the tooth would start hurting more.