Here, we investigated brain changes in 785 UK Biobank participants (aged 51–81) imaged twice, including 401 cases who tested positive for infection with SARS-CoV-2 between their two scans, with 141 days on average separating their diagnosis and second scan, and 384 controls.
It sounds like they had 401 cases where they had two scans with covid in between so in those cases at least you have a direct paired control. But yeah I'm also skeptical of how big of a practical effect this has on that many people. That being said we're fucking around and finding out about a virus we know little about getting all into our vital organs and causing our immune system to go wild.
They already controlled for that
That didn’t exactly clarify how they controlled for age factors
384 in the control group, maybe?
It sounds like they had 401 cases where they had two scans with covid in between so in those cases at least you have a direct paired control. But yeah I'm also skeptical of how big of a practical effect this has on that many people. That being said we're fucking around and finding out about a virus we know little about getting all into our vital organs and causing our immune system to go wild.