• hostilearchitecture [any]
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    edit-2
    2 years ago

    Biden is essentially correct :biden-alert: in that SARS-CoV-2 has mutated and is continuing to mutate for infectivity and not for causing severe illness. I suspect he's saying it, and they started suppressing case reporting, because they know how badly the vaccine program was fucked up. If there's enough distance between the Dems declaring it's ended and 2024 though, they can pin the failures on Trump (who started the development and fast track approval bullshit that led to the massive fuck up) and hopefully some of the people who start noticing will forget the Biden admin's full hog approach to mandating vaccines through OSHA and whatnot.

    If it were going to be "stopped", it had to happen years ago, close to its emergence. Like the original SARS virus. At this point you'd need a neutralizing vaccine, which is infeasible especially with so much of the population already imprinted with leaky spike protein antibodies. Unfortunately regulators were sold on a vaccine development strategy which could never be neutralizing, and rather than invest in something effective they're just going to keep throwing money at private companies that develop shit. If I hadn't seen the foundations of it, I'd assume the COVID anti-vax movement were funded by one or some of these pharma companies specifically to discredit any whistleblowers who might have come forward. Hell, they might've, might explain why the former chief scientist and vice-president of the allergy and respiratory research division at Pfizer was one of the principal conspiracy theorists in the anti-mask/lockdown/vaccine crowd from its inception. But I think he's actually just crazy, it's just plausible, that's all.

    And I know a thing or two about that shit, because I work on it, as a member of a firm that does concerningly large amounts of the clinical trial data science for pharma companies... I'm not really interested in losing the ability to keep billing Pfizer for their shitty shit, but if mods want to verify my position I'm happy to do so.

    There's almost no way out of the current situation though. A lot of peoples' bodies have memorized an antibody response for a years-old version of the virus which does not exist in humans today. And those memories can't be updated or overwritten, it's just not possible to do that today. Some people will probably keep getting infected repeatedly in all likelihood. I've seen it myself, my vaccinated colleagues seem to contract COVID-19 like clockwork. Others at my firm had chastised them for ignoring decades of literature and clear indications that this virus would mutate quickly and out of the vaccines' ability to neutralize infection. Somehow they're still able to market it, despite to my knowledge the Emergency Use Authorization having expired and their biologics marketing licensing being for PREVENTION of COVID-19, something it very clearly does not do. That's off-label use, and that's actually illegal. But they're getting away with it.

    • MF_BROOM [he/him]
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      2 years ago

      Does this mean I shouldn't pin my hopes on a universal or nasal vaccine? :doomjak:

      I mean I know this shit is gonna be with us for the rest of our lives in some capacity, but I was hoping that a universal or nasal vaccine could reduce the spread (and hopefully get less virulent over time) and make it more akin to how we view something like the flu, but I also obviously have no idea what the fuck I'm talking about. I just see quite a few epidemiologists and people from other adjacent professions increasingly beating the drum on these kinds of vaccines.

      • TheModerateTankie [any]
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        2 years ago

        Nasal vaccines will be usefull because they can head off infection before it gets into your blood stream, so spread would definately be reduced. The current vaccines target the virus once in the bloodstream. Future vaccines may be able to get around the imprinting problem. It's being worked on anyway. Best bet is to not get infected at all, but the "urgency of normal" is making that nearly impossible.

        • MF_BROOM [he/him]
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          edit-2
          2 years ago

          That seems like it would be much better for preventing long COVID too, if it stops infection before reaching one's blood stream, or in theory anyways.

          • TheModerateTankie [any]
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            2 years ago

            Covid getting into the bloodstream is what's causing so much organ damage, since it can attack pretty much every part of the body at that point. If we can head it off at the mucus membraines we would be much better off.

    • TheModerateTankie [any]
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      edit-2
      2 years ago

      From what I've read, we are seeing imprinting from repeat covid infections. Which is leading to people not developing antibodies to omicron variants leading to repeat reinfections within a short amount of time.

    • fitterr
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      edit-2
      1 year ago

      deleted by creator