I think its biggest problems were that it tried to riff on current news stories more than the original (though the original also did that a bit) and due to the delay between writing and a live release it's already dated by the time it airs, and that it stopped doing the obsessive continuity stuff that the original did where they'd keep track of different points to make sure they didn't contradict themselves with the characters or worldbuilding. It did have its moments though, I'll give it that. The eyePhone episode was gross and bad though, probably the worst episode of those seasons: it was trying to be topical, it invented a new bad character just to riff on, it broke established character traits, its entire plotline was a cliche that had been done countless times already (I'm not sure how "don't sell out your friends to become a shock-content rising star" is a story that gets repeated that often, and can only assume it's something hollywood writers feel like they need to tell people? It's such a weird niche thing to turn into a moral fable over and over), and it was gross in general.

The movies in between the original run and the comedy central seasons were probably the best the show got in terms of general quality imo.