Overall... not good!

  • duderium [he/him]
    ·
    1 year ago

    Nice, is there anything this virus doesn’t fucking destroy?

  • PolPotPie [he/him]
    ·
    1 year ago

    In autopsy tissue, mitochondrial gene expression had recovered in the lungs,

    geordi-yes

    but not in the heart, kidneys, and liver.

    geordi-no

    The rodent tissue and measurement of the time of peak viral load in the lungs showed that mitochondrial gene expression was suppressed in the cerebellum, even though SARS-CoV-2 wasn't found in the brain. The cerebellum coordinates and regulates muscle activity.

    Other animal models showed signs of recovery of mitochondrial function in the lungs during the mid-phase of COVID-19 infection.

    Co-senior author Douglas Wallace, PhD, of CHOP, said that the study offers strong evidence that COVID-19 is a systemic disease that affects multiple organs rather than strictly an upper respiratory illness. "The continued dysfunction we observed in organs other than the lungs suggests that mitochondrial dysfunction could be causing long-term damage to the internal organs of these patients," he said in the release.