Probably not, the US skirts the legal definition of a blockade by creating insane hoops to jump through. Countries that want to trade with Cuba can't use the SWIFT banking system, meaning no digital transactions, meaning they literally have to carry the cash with them to the island and back. They have to use ships that can't dock in US ports for 6 months after docking in Cuba (which Cuba having a gdp less than half a percent of US gdp means businesses have no incentive to choose trade with Cuba). And the trade has to be humanitarian, no military applications (but this also applies to medical and tech equipment which US says have "dual purpose"). All that said, there are awesome countries that choose to go through these hoops at significant cost and risk. But it takes a lot of time and planning to setup and get the right permits.
One can hope that other countries conclude to provide similar aid and relief to Cuba.
Brazil is already doing, Lula da Silva was organizing to send Oil and Food to Cuba. The Brazilian diplomat said they would follow Mexico's actions and channels to avoid the sanctions.
I am going to enter Comrade Xi's mind and implant thoughts to establish a couple container and tanker ships that only trade with Cuba so they don't have to deal with the blockade restrictions on docking in US ports. It will not be profitable, instead, every time Jack Ma gets a delusion of grandeur he gets fined another 5 billion RMB to fund this.