He had a solo Inebriated History episode about it. He explains how the singular point of the Constitution and the government it charted was, above all else, to prevent literal feudal war between landowners after the War of Independence. The bare framework of a liberal republic is to give the Property-Owning Class a means to settle disputes through laws and words instead of hurling armed peasants at one another. He points out that it only took about 3 generations for this one feature to fail, when the government prescribed by the Constitution failed to solve Slavery through legislation until a property war was declared. So the one thing the Constitution was actually supposed to do ... well, it didn't.

The entire system, including Congress and the Presidency and how elections would be run; they were all part of a series of compromises between Land Owners only interested in preserving their property ownership. It wasn't wise men sitting around trying to form the ideal government for everybody, only for themselves, and in a way that would specifically prevent the landless from gaining political power.

This all leads up to an explanation of how political parties don't even pretend to give a shit about common working people until the Great Depression (out of fear of a classd-driven revolution), and even then have to be dragged kicking and screaming into a faux populist electoral system by the 60's.

Mitch McConnel is able to single-handedly slam this system to a halt because it was never designed to be about two parties putting up difference performances for the people. The Constitution and the electoral system was only ever supposed to be a handful of very wealthy totally-not-feudal-lords politely arguing about who owns what river. And again, it couldn't even do that right.

Our system doesn't work the way we want it to because it was literally never designed to.
It's like being angry that a corporate mission statement about how to run executive board meetings doesn't provide any official means for the workers to raise their wages.

And as for the usual bleating of "The Founding Fathers didn't want a government that could be changed quickly," yes, that's true. It was not benevolence or some secret wisdom that made them think an unresponsive and sluggish government would be better for people; it was in their own words a means to prevent their workers and slaves from ever voting themselves out of poverty. It was to make sure their sacred property rights would never change in their lifetime, which was their only material concern.

If anyone can find and link the episode that would be great.