I’m sick and came to the doctor to get tested for covid, strep, and flu, since those are going around my work. I asked the doctor if I could get paxlovid if the covid test was positive, and he goes “Oh I don’t think you’d need it”

Motherfucker almost everyone who catches covid should be fucking taking it wtf is wrong with you. Oh I’m young and otherwise healthy? Yeah and I’d like to fucking stay that way thank you very much, and I’ll take any reduction in the chance of becoming permanently disabled.

Also of the medical professionals I saw today, they were only wearing surgical masks, not N95s and I can’t comprehend it. Why in the hell would you go into the room of a likely covid case not wearing an N95 are you insane?

I’m so fucking sick of being the only person in this entire town that’s actually worried about catching this disease, even the fucking doctors don’t care anymore. I work in a research facility attached to a hospital and when I go to the food court and shit at best like 1/25 people are wearing masks. In a hospital.

Thank you Mr Joe Brandon for ending the pandemic, you’ve truly cemented your place among history’s greatest killers.

covid-cool biden-harbinger covid-cool

  • a_blanqui_slate [none/use name, any]
    ·
    1 year ago

    Your point about carefully avoiding that we select for a resistant strain I think is especially powerful because even if an individual wants to roll the side-effects dice there is still community harm involved in that decision. You completely won me with that argument.

    Is there a viable biochemical pathway for this to develop? I don't fret about prophylactic use of hand sanitizer for fear of selecting an alcohol resistant strain, because that's not possible, or to put it more accurately, there is no plausible mutation that would lead to alcohol resistance being incorporated into the viral genome.

    and stay anchored in science.

    Show

    • FrogFractions [he/him, comrade/them]
      ·
      1 year ago

      Is there a viable biochemical pathway for this to develop

      I’m not a medical expert but a quick google search revealed medical experts fearing that is the case

      Also interestingly enough I decided to google if bacterial resistance to hand sanitizer was a thing and yes apparently some bacteria are evolving tolerance of hand sanitizer.

      Life will uh find a way

      • a_blanqui_slate [none/use name, any]
        ·
        1 year ago

        I’m not a medical expert but a quick google search revealed medical experts fearing that is the case

        Just like there were medical experts sharing that masks were not effective for the general public at the opening stages of the pandemic.

        Also interestingly enough I decided to google if bacterial resistance to hand sanitizer was a thing and yes apparently some bacteria are evolving tolerance of hand sanitizer.

        Bacterial 'resistance' to ethanol based hand sanitizer is not a thing so much as bacterial tolerance of alcohol concentrations can increase, and they can point to the specific biochemical pathways of concern (changes to carbohydrate metabolism). Which is not the case and cannot be the case for a lipophilic virus like SARS-CoV-2.

        A quick glance at the literature indicates:

        1. There are observed mutations in the main proteases that confer resistance to paxlovid [1][2]
        2. These confer significant fitness penalties to the virus outside of paxlovid exposure. [2]
        3. Due to point 2 and the rarity of these mutations, these are not expected to occur in a meaningful level outside of selection internal to immunosupressed individuals [2][3].

        Yeah imma get the drug.