Here's what we know.

Here's a good breakdown on nasal sprays for covid, and other viruses for that matter.

All of these sprays work by forming a protective barrier in your nasal cavity that blocks viruses from binding with the ACE-2 receptors. Most research agrees that your nose serves as the primary gateway for infections.

It's the landing ground.

From there, you aspirate viral particles into your lungs. If you can block, deactivate, or kill pathogens in your nose, then you prevent an infection before it gets going.

The rest of the article goes into how they work and what we know about how effective they are.

I wouldn't trust them that much in crowded indoor public space, but if you are hanging out with friends and none of them are symptomatic of anything it certainly helps lower your risk.

  • Southloop [he/him]
    ·
    11 months ago

    Got any good recommendations on where to track the progress on new upper airway vacs/those Finnish trimeric sprays in the works?

    Thanks for the post. I follow the PLOS blog, but this month’s update was preempted by a medical conference it looks like. My spouse has a benign brain tumor so we’re hunting for some hope and (eventual) peace of mind.

    • TheModerateTankie [any]
      ·
      11 months ago

      I hadn't heard of it, and there doesn't seem to be much news on the trimeric spray. It looks like it's an actual vaccine, so it will probably be a while before it's approved. I know one of the goals of the nasal vaccines is to stop an infection at the mucosal layer before it gets into the bloodstream, so that would be a big improvement in decreasing the danger of the virus and preventing transmission, but no one has pulled it off yet.

      The list of sprays above are temporary sprays ment to block the ability for viruses to infect the nasal passage for a few hours, so there isn't a strict protocol for approval.

        • Southloop [he/him]
          ·
          11 months ago

          I see. Well, thanks for the article. It helps. I’ll keep an eye out for it (TrisB92 is the name, BTW).

          In the interest of info propagation, here’s what I’ve been working with:

          https://absolutelymaybe.plos.org/2023/09/30/a-bumper-news-month-for-next-generation-covid-vaccines-update-11/