Do they agree with you on anything except one or two extremely propagandized wedge issues? Then you can probably work on them overcoming these one or two cases of brainworms and turn them into a comrade.
Do they agree with you on one or two issues that directly benefit them and are otherwise fully indoctrinated, committed status quo supporters? Then don't waste your time with them.
Same as with liberals:
Do they agree with you on anything except one or two extremely propagandized wedge issues? Then you can probably work on them overcoming these one or two cases of brainworms and turn them into a comrade.
Do they agree with you on one or two issues that directly benefit them and are otherwise fully indoctrinated, committed status quo supporters? Then don't waste your time with them.