https://www.medrxiv.org/content/10.1101/2022.03.20.22272571v1.full.pdf

For first infections, 19% of cases were associated with hospital admissions.

For second infections, 17% of cases were associated with hospital admissions - not a very significant difference.

For third infections, 25% of cases were associated with hospital admissions.

The authors also found an 8x increase in reinfection during the beginning of Omicron, from November 2021 to January 2022. This was the highest raw increase in reinfections, but the highest rate was just at the beginning of the Delta wave in Spring, 2021.

The authors note that this data is a lower bound.

So not only does reinfection not give you protective immunity, it actually increases your chance of catching it again, and getting a more severe infection. This means that not only is the herd immunity strategy pointless, but it's also actually actively making things worse over time compared to not doing it. Shitty both in the short term and long term.

https://www.medrxiv.org/content/10.1101/2021.07.22.21260972v2.full.pdf

This study, combining 81 different studies in 22 different countries, reported a 3x increased hospital admission rate on reinfections, and a doubling of the number of patients who needed oxygen.

  • Dirt_Owl [comrade/them, they/them]
    ·
    3 years ago

    It seems that covid does lasting damage to the body and reinfecting will add to that damage.

    Crippling an entire genration for line go up

  • Mehrunes_Laser [comrade/them, any]
    ·
    3 years ago

    Human beings are responsible for the decisions that will have left millions dead or disabled. The term "furious" doesn't even come close to how I feel.

  • KiaKaha [he/him]
    ·
    3 years ago

    For third infections, 25% of cases were associated with hospital admissions.

    Couldn’t this be because the only people getting reinfected three times are those with severe immunodeficiencies?

    • SeventyTwoTrillion [he/him]
      hexagon
      ·
      3 years ago

      Perhaps, but that doesn't help much if "being infected with coronavirus" counts as an immunodeficiency (and, given how much it fucks up everything else in your body, and how many things count as "pre-existing conditions", it might as well be)

      • KiaKaha [he/him]
        ·
        3 years ago

        I mean, that would explain the hospitalisation rate.

        Immune systems that struggle to gain immunity after two infections likely also are predisposed to end up hospitalised once the infection takes hold.

        That’s not to say you want to catch it, or that society shouldn’t be trying to fight the virus.

  • CheGueBeara [he/him]
    ·
    3 years ago

    Does the studies account for behavior? There's been a trend towards riskier behavior over time due to shit regulations.

  • kristina [she/her]
    ·
    edit-2
    3 years ago

    Was true for me. Second covid even with vaccine fucked me up. Got it end of December only just now feeling right again

    I shudder to think what it'd be like without the vaccine

    • Ghoucckyoou [none/use name]
      ·
      edit-2
      3 years ago

      Nobody knows what's going on, the first time I had COVID I had no idea whatsoever and only knew from an antibody test in Jul 2020 during routine blood work when I requested it. Never bothered getting vaccinated since the nucleocapsid antibodies were still detectable at high levels in May 2021.

      Then I had it again in Dec 2021 after the holidays, my brother-in-law had a positive test after feeling somewhat bad, I had a stuffy nose the day I was informed of that test and we were right next to each other for a few days during that time so I'm fairly sure it was probably COVID again. Then my fiance had it (confirmed with a PCR test at least) in mid-Feb 2022 and was fairly sick (3rd dose of Pfizer/BioNTech's product taken in early Jan) for about 2 days but I never got anything and we took 0 precautions against me getting it.

      There's too many variables and there's definitely some genetic factors/how much viral load you were exposed to coming into play.

      • kristina [she/her]
        ·
        edit-2
        3 years ago

        I got complete devastated both times but my oxygen levels were fine all throughout. The worst part was eating because when I ate itd put pressure on my lungs and it hurt a fuckton when that happened so I tried to just eat little snacks all the time

        I might just have a hyperactive immune system and thats the big reason I feel so terrible for so long

      • sooper_dooper_roofer [none/use name]
        ·
        edit-2
        3 years ago

        Nobody knows what’s going on

        I was saying this in 2020, but I didn't think I'd be saying it in 2022. People literally don't know anything.

        Also I had an extremely bad case at the start of the pandemic, and had long COVID for a year until 2021. I've basically been isolating for two years (neet lul) and I'll say that I feel noticeably better this year than even last year (when I felt pretty much cured of long COVID).

    • SeventyTwoTrillion [he/him]
      hexagon
      ·
      edit-2
      3 years ago

      I don't know for sure. To give a guess, I'd imagine that vaccinated people would do better. But I'd also say that vaccination would only really matter if it was ~6 months ago, so as long as you're keeping yourself topped up with boosters, then you should be fine. As well as mask wearing and all that to decrease your odds too.

      Nature recently found that, in the context of BA1 vs BA2, "a study published on 13 March shows that mRNA vaccines offer a similar degree of protection against the two strains — although protection against SARS-CoV-2 infection and symptomatic disease wanes within months of a third dose." The timescale is that after 4-6 months, there's an average of 10% protection remaining. However, that's only overall - if you consider just severe symptoms then the vaccines give you better protection for much longer: "This analysis showed that protection against severe disease remained at 68% or higher for at least 7 months, even in people who had only received two vaccine doses, and shot up to over 80% after a booster dose."