It's a startling statistic: A new study finds the number of kids accidentally poisoned by the over-the-counter sleep aid melatonin has soared by 530% over the past decade.
The melatonin and i-pad time generation is gonna be deeply unwell holy
i've been tapering for a month now. it's unreal how much they put in capsules and how little quality control there is. i finally found some low dose liquid shit which i basically dose by taking a tiny droplet on my tongue. about 10 micrograms
Interesting. There are unfortunately a few cursed individuals for whom it seems certain serotonergic (and apparently melatonergic) drugs simply do not function. I vaporized DMT with a guy who was completely unaffected by that and cannabis. He claimed absolutely no change in his cognition or perception after inhaling and holding in a dosage that sent me to a space occupied by an ethereal duck-god and its array of unrecognizable/incomprehensible machinery. I have a lot of sympathy for those afflicted with such exceptional responses to these tools.
I'm overwhelmingly sensitive to everything else, especially Cannabis, so it's probably more complicated than that. Never done DMT but Salvia sent me to the building blocks of reality of few times. seems specific to melatonin. I have a bonafide sleep disorder though with insomnia that'll keep me up for days at a time, so I always assumed it was related to that.
In https://news.mit.edu/1999/melatonin-1103 , "She also said that one of the trickier aspects of choosing an appropriate dose of melatonin for use as a sleep aid is that "normal" melatonin levels vary widely among individuals and the same dose of the hormone can induce different levels depending on the individual's age or health. She recommends measuring individual melatonin levels, or, if this is not feasible, starting with a tiny dose (0.1 mg) and gradually increasing it until the desired effect is noticed."
I don't think the SFN publishes their talks and posters as journal articles and I had trouble finding the paper I remembered from my stint as a neuroscience grad student years ago. In that article, they ran an experiment whose goal was identifying minimum effective dosages in humans and came up with 100 micrograms as a dose that works for most people, with the vast majority (i.e., > 95%) of people responding to 300 micrograms.
Melatonin is packaged in doses that are quite literally 10 to 100 times larger than the minimum effective dose in a large adult human.
edit to add: it's also a powerful psychoactive drug that's treated like a vitamin
i've been tapering for a month now. it's unreal how much they put in capsules and how little quality control there is. i finally found some low dose liquid shit which i basically dose by taking a tiny droplet on my tongue. about 10 micrograms
Lol it’s done nothing to me and I’ve taken like 30 mg at a time
be me:
take way too much coffee to stay awake at work :maduro-coffee:
also be me:
take way too much melatonin to fall asleep at night :lenin-sleeping:
:agony-limitless:
Are you taking SSRIs or other serotonergic/melatonergic drugs?
I'm in the same boat as the person you're replying to and the answer for me is no.
It just doesn't effect me
Interesting. There are unfortunately a few cursed individuals for whom it seems certain serotonergic (and apparently melatonergic) drugs simply do not function. I vaporized DMT with a guy who was completely unaffected by that and cannabis. He claimed absolutely no change in his cognition or perception after inhaling and holding in a dosage that sent me to a space occupied by an ethereal duck-god and its array of unrecognizable/incomprehensible machinery. I have a lot of sympathy for those afflicted with such exceptional responses to these tools.
I'm overwhelmingly sensitive to everything else, especially Cannabis, so it's probably more complicated than that. Never done DMT but Salvia sent me to the building blocks of reality of few times. seems specific to melatonin. I have a bonafide sleep disorder though with insomnia that'll keep me up for days at a time, so I always assumed it was related to that.
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Nah I dig the crazy dreams
Why not just take 1mg or split the 1mg in two?
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Ah, i can’t read for shit, thought it was not poisoned kids selection, but using melatonin
Source?
In https://news.mit.edu/1999/melatonin-1103 , "She also said that one of the trickier aspects of choosing an appropriate dose of melatonin for use as a sleep aid is that "normal" melatonin levels vary widely among individuals and the same dose of the hormone can induce different levels depending on the individual's age or health. She recommends measuring individual melatonin levels, or, if this is not feasible, starting with a tiny dose (0.1 mg) and gradually increasing it until the desired effect is noticed."
I don't think the SFN publishes their talks and posters as journal articles and I had trouble finding the paper I remembered from my stint as a neuroscience grad student years ago. In that article, they ran an experiment whose goal was identifying minimum effective dosages in humans and came up with 100 micrograms as a dose that works for most people, with the vast majority (i.e., > 95%) of people responding to 300 micrograms.