Mine is probably the most boring: There are many intelligent species in the universe. Faster-than-light travel, however, really is simply impossible, meaning that there cannot exist a truly interstellar civilization. So while some species have probably settled solar systems other than their own through generation ships, suspended animation, time dilation, or whatever, their range of expansion is limited. This means that encounters between species of different planets are rare. Humans will most likely never contact any intelligent alien species, at most one or two. We might, however, discover evidence of their existence through telescopes or something.
This is a wild assumption to make. Fuck's sake, we're not a space faring civilization. Let's say space is an ocean - we're a civilization that has gone up to the shore and walked around in the tide - arguably we've done a bit of swimming but we're still right up against the shore, and has launched a few messages in a bottle in the hopes that maybe someone will find them. We're not a space faring civilization.
Yeah, for sure, when you're thinking about it in terms of a human lifespan. But the time scale we're talking about is insanely huge. So your argument doesn't make much sense.
The current estimate for when life on earth began is actually 3.5 billion years. But I was being generous with the numbers. In this timeline, we have 1.5 billion years left to become space-faring. You gotta remember the scale, man.