I've been seriously considering estrogen/anti-T HRT, and reading other people's experiences the mental effects seem the most appealing to me as opposed to the physical side (not that those seem unappealing tho). I'd love to hear people's experiences here of how HRT has affected their emotions/cognition/sensory perception/connection to the cosmos/etc.
I've been on HRT for just short of a month, and already I'm feeling my depersonalization and derealization lifting. I don't have frame of reference to say if it's entirely gone, but I can definitely feel way more emotion than I could before. That's not always good- my long-term partner and I split up during that period, right in time for it to make me sadder than I've ever been in my life. But even that was kind of a relief in a weird way- being that sad is still better than being numb.
From his phrasing, it sounds like you might be considering trying T blockers without estrogen? I wouldn't recommend that- not having an androgen or an estrogen supposedly creates really bad mental health effects.