I most often play Pathfinder, with a mostly-canon Golarion setting. I almost always play a woman - sometimes I make her trans, and sometimes I don't. Her trans status is usually based on the rest of their characteristics, and whether I feel it "makes sense" for my character to realize she's trans.
When I played a brash, independent sorceror, or a young noblewoman with resources and connections and a supportive family, it made sense to make my characters trans because they were in a position to figure that out and had the ability to do something about it. In my current Pathfinder game, my character was raised in a militaristic cult that isn't a good environment for deep introspection, so I made her cis.
When I made my character for Baldur's Gate 3, she was a self-insert alongside my BF's self-insert, so she was transfemme and it was an easy decision. I'll generally prefer to make trans characters, but only if I can make up a good justification to do so.
I recently spoke to a friend who primarily makes cis woman characters as part of the whole "power fantasy" that comes with roleplaying, and her experience was a little different than mine, so I thought I'd ask here. Trans Hexbears, are your RPG characters trans?
I tend to pick depending on the type of character I'm going for. As such I got a roughly 50/50 split fem/masc for characters. I haven't actually played an explicitly trans character since I very rarely get to be a player in RPGs. Literally the last time (ignoring oneshots) was 4 years ago now, and I only realised I was trans near the end of that campaign. I've had a character made ever since then that I intend to play eventually who was basically my attempt to work through those feelings at the time. But she was cis and I was doing it through allegory, and kinda loosely at that. (And at this rate I'm probably never going to be able to play her besides)
If we count my NPCs that I run when GMing, I play basically everything by necessity. Though I tend to enjoy playing fem NPCs more, cis or trans.