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It means never trust a fart and they trusted that fart and look where it got them.
You misheard them. They said "oooh, it's cheese" excitedly at a restaurant — the fart had nothing to do with it
They got pinworms and are about to start dragging their ass on the carpet like a dog
They want someone to itch it for them but they're too shy to directly ask
it means they're trying to blame it on Itchy who never did anything wrong