idk shit about science, but I thought I would post it here. I hope it's true.
this article discusses monoclonal antibodies, which is a great treatment option for immunocompromised people. but monoclonal Ab treatment is more expensive by an order(s) of magnitude than a vaccine.
for general use in the population of ppl with complete immune systems, this research could be relevant in vaccine design. the antibodies in this paper bind to surface proteins on the virus. the mRNA in current covid vaccines is really good at activating our immune system, so future vaccines could contain a conjugate of the protein appended to the mRNA to utilize the immunogenicity (its ability to stimulate immune system) of the mRNA and the efficacy and effectiveness of the protein
edit: that being said, we are years from this work being used in an approved vaccine. you want to make sure the immune response to these conjugate vaccines doesn’t provoke deadly amounts of inflammation, whether the Abs it produces work against the protein or if the mRNA “hijacks” the response, what kind of immune response it produces, etc.
EILI5: Triggering a response of the immune system is a delicate thing because too much inflammation is a whoopsie daisy.
“Don’t let the cure be worse than the disease,” is supposed to be about medical treatments, not wearing a mask to the grocery store.
the discovery in the paper is a good treatment for ppl with immune disorders. but this discovery can also help make a better vaccine that activates the immune system as well as the current mRNA vaccines but has improved ability to cause ur immune system to kill covid. but it’s also a long ways away bc a lot of testing is required to ensure it’s safe and more effective than current vaccines
https://xcancel.com/sailorrooscout/status/1832073394994479312
🤞 But I would be wary about getting my hopes up too much. Things like this require mass adoption or you're basically just applying selective pressure to evolve. At this point, the big bad that is always going to need to be defeated for any of this to stop is capitalism.
tbh they should make seasonal covid vaccines but call it the “SARS vaccine”. but i think chuds would catch on eventually. maybe if they use this discovery to make a new protein-mRNA conjugate vaccine they can say it’s not an mRNA vaccine and they could sit down with trump and stroke his ego till he goes on tv and says it’s a really good, safe vaccine. but even then, antivax ppl are very set in their ways
or we could have a revolution and make full vaccinations mandatory
I think the barn door has closed on getting right wingers to vax (without force) for quite some time. I went searching for covid conscious communities on facebook the other day to see if i could find something local and came across a "Doctor" still being antivax and recommending ivermectin. These people need to be arrested.
Look at this shit.
https://www.facebook.com/photo/?fbid=26225862063724594&set=a.103447719726052
I think the anti-Covid vax nonsense has made it so a lot of people wouldn't take *any *future vaccine. Even if it were an even more deadly virus, even if right wing media wanted to push it, most of them are just too brainwormed now.
Since all the tech cultists are moving to Austin I don’t trust anything coming out of that place
And some Voodoo Donuts, but not the original ones from Portland. And you have to eat them under the Willie Nelson statue.
You can also only get the donuts if you turn a profit on at least 5 successful drug deals in the roof topiary at the Austin public library and reinvest 15% of your profit into an Uber over to the Alamo Drafthouse to watch an old kung fu movie
In Neoliberal America, even the ditchweed is means-tested
and im jebus